Some patients with severe acute respiratory distress syndrome (ARDS) experience hypoxemia during lung-protective ventilation, refractory to a fraction of inspired oxygen of 1.0 and high levels of positive end-expiratory pressure. Management options for refractory ARDS are discussed, including neuromuscular blocking agents (NMBA), prone positioning, inhaled pulmonary vasodilators, high-frequency oscillatory ventilation (HFOV), and extracorporeal membrane oxygenation (ECMO).
New research is the lifeblood of medical progress. Thanks to the proliferation of more than 50 good-quality medical journals publishing articles in critical care and respiratory medicine every month, most well-conducted research today will find publication. But will it be read? The sheer numbers of published articles and the extent of their dispersion have made […]